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Hemodynamic and cardiac metabolic changes during nicardipine-induced myocardial ischemia
A R Thomassen1, J P Bagger, T T Nielsen
1Aarhus Kommunehospital, Department of Cardiology, Denmark.
Catheterization and Cardiovascular Diagnosis
|January 1, 1988
Abstract:
After 10 mg nicardipine IV a patient with stable angina developed chest pain and ST-segment depression accompanied by excessive tachycardia, low arterial blood pressure, and initially decreased coronary sinus blood flow. Measurements of arterial concentrations and cardiac exchanges of lactate, glucose, free fatty acids, glutamate, and alanine showed alterations indicative of severe ischemia.