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In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
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Prediction modelling of COVID using machine learning methods from B-cell dataset.

Nikita Jain1, Srishti Jhunthra1, Harshit Garg1

  • 1Department of Computer Science & Engineering, Bharati Vidyapeeth's College of Engineering, 110063 New Delhi, India.

Results in Physics
|January 26, 2021
PubMed
Summary

This study predicts SARS-CoV and SARS-CoV-2 using B-cells data and machine learning. Ensemble strategies achieved high accuracy, aiding in early detection of these coronaviruses.

Keywords:
AdaBoostB-cellsCOVD-19CoronavirusEnsemblesGradient boostingK – nearest neighbors (KNN)Logistic regressionMultilayer perceptron (MLP)Naïve BayesRandom forestSARS-CoVSARS-CoV-2Support vector machine (SVM)XGBoost

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Area of Science:

  • Immunology
  • Infectious Diseases
  • Computational Biology

Background:

  • Coronaviruses, including SARS-CoV and SARS-CoV-2, have caused a global pandemic with significant mortality.
  • Accurate and timely prediction of coronavirus infections is crucial for disease management.

Purpose of the Study:

  • To predict the presence of SARS-CoV and SARS-CoV-2 using a B-cells dataset.
  • To evaluate the effectiveness of various machine learning and ensemble learning strategies for coronavirus prediction.

Main Methods:

  • Utilized a B-cells dataset for predicting SARS-CoV and SARS-CoV-2.
  • Applied diverse machine learning models: SVM, Naïve Bayes, K-nearest neighbors, AdaBoost, Gradient Boosting, XGBoost, Random Forest, and Neural Networks.
  • Developed and tested ensemble learning strategies to enhance prediction accuracy.

Main Results:

  • The proposed algorithm achieved an AUC score of 0.919 and 87.248% validation accuracy for SARS-CoV prediction.
  • For SARS-CoV-2 prediction, the algorithm yielded an AUC score of 0.923 and 87.7934% validation accuracy.
  • Ensemble learning strategies demonstrated significant benefits in predictive performance.

Conclusions:

  • Machine learning, particularly ensemble methods, can effectively predict SARS-CoV and SARS-CoV-2 using B-cells data.
  • The developed prediction models show high accuracy, supporting potential applications in early disease detection.
  • This approach offers a valuable tool for identifying individuals infected with these coronaviruses.