Using the RETeval Device in Healthy Children to Establish Normative Electroretinogram Values

Area of Science:

• Ophthalmology
• Clinical Electrophysiology
• Pediatric Eye Care

Background:

• Establishing normative electroretinogram (ERG) values is crucial for diagnosing pediatric retinal disorders.
• The RETeval device offers a handheld, non-anesthetic option for pediatric ERG testing.

Purpose of the Study:

• To generate normative full-field electroretinogram (ERG) data in healthy children using the RETeval device.
• To assess the correlation between age and ERG parameters in the pediatric population.

Main Methods:

• A cross-sectional study involving 20 healthy children (ages 4-17) with normal fundus examinations.
• Full-field ERGs were recorded using the handheld RETeval device and skin electrodes, following the ISCEV 5-step protocol.
• Both photopic and dark-adapted scotopic responses were measured.

Main Results:

• Normative mean, median, and range values for full-field ERG parameters were established.
• Moderate positive correlations were found between age and oscillatory potential/scotopic dim flash amplitude (r=0.59).
• A strong positive correlation was observed between age and cone a-wave implicit time (r=0.67).

Conclusions:

• The RETeval system is effective for obtaining pediatric full-field ERGs without anesthesia.
• The study provides essential normative ERG data for children.
• Age-related correlations highlight developmental changes in retinal function detectable by ERG.