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COVID-19 in Children with Asthma

Grigorios Chatziparasidis1, Ahmad Kantar2

  • 1Primary Cilia Dyskinesia Unit, School of Medicine, University of Thessaly, Thessaly, Greece. gchatziparasidis@gmail.com.

Lung
|January 26, 2021
PubMed

Insights

Children infected with SARS-CoV-2 generally experience milder illness. Asthmatic children infected with the virus exhibit even less severe symptoms compared to adults, suggesting protective mechanisms at play.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Respiratory Medicine

Background:

  • Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) affects all age groups.
  • Children infected with SARS-CoV-2 typically present with less severe disease than adults.
  • Asthmatic children appear to have milder SARS-CoV-2 infections compared to adults.

Purpose of the Study:

  • To review the interaction between SARS-CoV-2 and childhood asthma.
  • To summarize current knowledge on mechanisms ameliorating SARS-CoV-2 disease in asthmatic children.

Main Methods:

  • Literature review of epidemiological and clinical data.
  • Analysis of studies investigating SARS-CoV-2 infection in pediatric populations.
  • Synthesis of research on asthma and viral respiratory infections.

Main Results:

  • Children generally have better outcomes with SARS-CoV-2 infection.
  • Asthmatic children demonstrate a trend towards milder SARS-CoV-2 symptomatology.
  • Potential protective mechanisms in asthmatic children warrant further investigation.

Conclusions:

  • Asthma may confer a protective effect against severe SARS-CoV-2 disease in children.
  • Understanding these mechanisms could inform therapeutic strategies for both asthma and viral infections.

Keywords:
AsthmaCOVID-19ChildrenSARS-CoV-2

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