Multifocal Orthokeratology versus Conventional Orthokeratology for Myopia Control: A Paired-Eye Study

Area of Science:

• Ophthalmology
• Optometry
• Pediatric Eye Care

Background:

• Myopia, a refractive error, is a growing global health concern, particularly in children.
• Orthokeratology (OK) lenses are used to correct myopia and slow its progression.
• Novel multifocal orthokeratology (MOK) lens designs aim to enhance myopia control efficacy.

Purpose of the Study:

• To compare the efficacy of a novel multifocal orthokeratology (MOK) lens versus conventional orthokeratology (OK) lens in slowing axial eye growth in myopic children.
• To evaluate the impact of MOK lenses on ocular biometry over an 18-month period.

Main Methods:

• A prospective, paired-eye, investigator-masked study involving 30 children (ages 10-14) with myopia (-1.25 D to -4.00 D).
• Participants wore an MOK lens in one eye and a conventional OK lens in the fellow eye nightly for 18 months.
• Axial eye growth was monitored using non-contact ocular biometry.

Main Results:

• MOK-treated eyes exhibited significantly less axial expansion (0.173 mm less) and inner axial length change (0.156 mm less) compared to OK-treated eyes (p < 0.01).
• The reduction in eye elongation by MOK lenses was consistent across various baseline myopia progression rates.
• Visual acuity was reduced in MOK-treated eyes compared to OK-treated eyes at six months (p = 0.01).

Conclusions:

• Multifocal orthokeratology (MOK) lenses demonstrate superior efficacy in reducing axial eye growth compared to conventional orthokeratology (OK) lenses over 18 months.
• MOK lenses represent a potentially more effective therapeutic option for myopia control in children.
• Further research is warranted to optimize MOK lens parameters and assess long-term visual outcomes.