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[Prevalence of diabetes and associated factors in Hainan centenarians]

M Liu1, S S Yang2, S S Wang2

  • 1Department of Statistics and Epidemiology, Graduate School, Chinese People's Liberation Army General Hospital, Beijing 100853, China；Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital,Beijing 100853, China.

Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi
|January 27, 2021
PubMed

Insights

Diabetes prevalence in Chinese centenarians is 9.5%, with impaired fasting glucose affecting 8.1%. Glycometabolism in this group is notably better than in younger populations, with no gender-specific differences observed.

Area of Science:

  • Gerontology
  • Endocrinology
  • Epidemiology

Background:

  • Centenarians represent a unique demographic for studying aging and age-related diseases.
  • Understanding diabetes prevalence and risk factors in extreme longevity is crucial for public health.
  • Hainan province in China has a significant centenarian population, offering a valuable cohort for research.

Purpose of the Study:

  • To determine the prevalence of diabetes and impaired fasting glucose (IFG) in centenarians.
  • To identify factors associated with glucose metabolism abnormalities in this elderly population.
  • To compare glycometabolism in centenarians with other age groups.

Main Methods:

  • Analysis of data from the China Hainan Centenarian Cohort Study.
  • Inclusion of 1,002 centenarians categorized into diabetes, IFG, and normal glucose groups.
  • Assessment of fasting plasma glucose (FPG) levels, triglyceride levels, and abdominal obesity.

Main Results:

  • The prevalence of diabetes was 9.5% and IFG was 8.1% among the 1,002 centenarians.
  • The mean FPG level was 5.12±1.44 mmol/L, with 43.5% having FPG between 4.00-5.00 mmol/L and 22.1% between 5.00-6.00 mmol/L.
  • Increased triglyceride levels and abdominal obesity were potentially associated with a higher risk of diabetes.

Conclusions:

  • Centenarians in Hainan exhibit better glycometabolism compared to younger individuals.
  • No significant gender-specific differences in glycometabolism were observed in this centenarian cohort.
  • The findings suggest unique metabolic adaptations in extreme aging.

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