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[Distribution characteristics of blood lipid profile in Hainan centenarians]

S S Wang1, S S Yang1, W P Jia1

  • 1Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital,Beijing 100853, China.

Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi
|January 27, 2021
PubMed

Insights

The prevalence of dyslipidemia in Hainan centenarians is low, with higher blood lipid levels observed in females. Key influencing factors include smoking, BMI, and area distribution.

Area of Science:

  • Gerontology
  • Cardiovascular Health
  • Biochemistry

Background:

  • Centenarians represent a unique population for studying aging and health.
  • Understanding lipid profiles in extreme longevity is crucial for public health.
  • Dyslipidemia is a significant risk factor for cardiovascular diseases.

Purpose of the Study:

  • To determine the prevalence of lipid profiles and dyslipidemia in Hainan centenarians.
  • To identify factors influencing dyslipidemia in this population.
  • To provide baseline data for future research on centenarian lipid metabolism.

Main Methods:

  • Analysis of baseline data from the China Hainan Centenarian Cohort Study (2014-2016).
  • Inclusion of 1,002 centenarians.
  • Assessment of lipid profiles (TC, TG, LDL-C, HDL-C) and dyslipidemia prevalence based on Chinese adult guidelines.

Main Results:

  • Median lipid levels: TC 4.60, TG 1.05, LDL-C 2.77, HDL-C 1.41 mmol/L.
  • Females exhibited higher blood lipid levels than males.
  • Dyslipidemia prevalence was 19.1%, influenced by smoking, BMI, and geographic distribution.

Conclusions:

  • Hainan centenarians show a low prevalence of dyslipidemia compared to global averages.
  • Sex differences in blood lipid profiles are notable in this centenarian cohort.
  • Identifying influencing factors like BMI and smoking can inform targeted health interventions.

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