Related Experiment Video
Updated: Jun 30, 2026

Isolation and Profiling of MicroRNA-containing Exosomes from Human Bile
Published on: June 13, 2016
Profiling of Bile Microbiome Identifies District Microbial Population between Choledocholithiasis and
Rungtiwa Dangtakot1,2, Kitti Intuyod2,3, Anucha Ahooja4
1Biomedical Sciences Program, Graduate School, Khon Kaen University, Nai Mueang, Khon Kaen, Thailand.
Objective:
Choledocholithiasis (CDL), a potential risk for cholangiocarcinoma (CCA) development, is often a consequence of bacterial infection. Thus, the microbial population that contributes to CDL might also be involved in CCA development. We compared the microbiome in bile fluid of CDL patients and CCA patients.
Methods:
Bile samples were collected from CDL (n = 30) and CCA (n =30) patients. Microbial profiling was performed individually by the sequencing of V3-V4 regions of the 16S rRNA gene.
Results:
Enterobacter, Pseudomonas, and Stenotrophomonas species were much more abundant in bile samples from CCA compared to CDL (p.
Related Concept Videos
Microbiota of the Stomach and Small Intestine
Microbiota of the Large Intestine
Dysbiosis of the Gut Microbiota

