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Updated: Jun 8, 2026
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Isolation and Characterization of Mouse Antral Oocytes Based on Nucleolar Chromatin Organization
Published on: January 7, 2016
Anonymous and non-anonymous oocyte donation preliminary results
A M Junca1, J Cohen, J Mandelbaum
1Clinique Marignan, Paris, France.
Human Reproduction (Oxford, England)
|January 1, 1988
Summary
Oocyte donation offers a successful treatment for women with ovarian failure. This program achieved a 20% pregnancy rate per cycle using donated eggs for infertile patients.
Area of Science:
- Reproductive Medicine
- In Vitro Fertilization
- Oocyte Donation
Background:
- Infertility due to ovarian failure requires alternative reproductive solutions.
- Oocyte donation is a viable option for women unable to produce viable eggs.
Purpose of the Study:
- To evaluate the efficacy of an oocyte donation program for patients with absent endogenous ovarian function.
- To establish a protocol for oocyte donation in cases of premature ovarian failure, castration, and Turner's syndrome.
Main Methods:
- Oocyte donation program involving 10 patients with ovarian failure.
- Anonymous and non-anonymous oocyte donors were utilized.
- Embryo transfer was performed either fresh or after cryopreservation and thawing.
Main Results:
- Twenty cycles were performed in 10 patients.
- Thirteen embryo transfers resulted in four clinical pregnancies.
- Pregnancy rates were 20% per cycle and 31% per transfer, with successful outcomes in premature ovarian failure and Turner's syndrome patients.
Conclusions:
- The oocyte donation program demonstrated promising results for treating infertility in women with ovarian failure.
- The established protocol warrants further development and application.
