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Histiocytosis X with scoliosis and osteolysis

R R Wroble1, S L Weinstein

  • 1Department of Orthopaedics, University of Iowa Hospitals, Iowa City 52242.

Journal of Pediatric Orthopedics
|March 1, 1988
PubMed

Histiocytosis X can exhibit a variety of musculoskeletal manifestations. Nonetheless, this case exhibits two striking features. Severe progressive scoliosis and massive osteolysis of both femoral shafts occurred in conjunction with the Hand-Schüller-Christian form of histiocytosis X. The scoliosis was treated successfully by posterior fusion and instrumentation. The clinical features of histiocytosis X are reviewed. Speculation as to the etiology of these features is presented.

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