Related Experiment Video
Updated: Nov 19, 2025
07:13
Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
4.7K
Leveraging Mobile Sensing to Understand and Develop Intervention Strategies to Improve Medication Adherence
Anna N Baglione1, Jiaqi Gong2, Mehdi Boukhechba1
1Department of Engineering Systems and Environment, University of Virginia.
IEEE Pervasive Computing
|January 29, 2021
Summary
This study introduces a new framework for medication adherence research, using mobile sensing to understand patient behavior in real-world settings. This approach aims to create personalized interventions for better medication adherence.
Area of Science:
- Digital Health
- Behavioral Science
- Translational Science
Background:
- Traditional medication adherence interventions show limited success and high resource demands.
- A paradigm shift is occurring towards personalized, theory-driven interventions for medication adherence.
- Mobile and wearable sensing offer novel opportunities to study medication-taking behaviors in naturalistic settings.
Purpose of the Study:
- To present a novel transdisciplinary research framework for medication adherence.
- To highlight critical advances in the rapidly evolving field of medication adherence research.
- To outline future research and clinical application directions for medication adherence.
Main Methods:
- Integrating foundational and translational science for a mechanisms-focused, context-aware approach.
- Utilizing mobile and wearable sensing systems to capture medication-taking behaviors in situ.
- Combining sensor data with survey and ecological momentary assessment data.
Main Results:
- Mobile and wearable sensing systems can directly capture the context of medication adherence.
- These systems provide insights into personal, behavioral, and environmental factors influencing adherence.
- The approach facilitates understanding of medication-taking behaviors in real-world settings.
Conclusions:
- A new transdisciplinary framework integrating mobile sensing enhances understanding of medication adherence.
- This context-aware approach offers personalized intervention potential for improved adherence.
- Future directions include leveraging technology for advanced medication adherence research and clinical practice.
Related Concept Videos
01:28Drug Therapy
154
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
154
01:29Therapeutic Drug Monitoring: Affecting Factors
86
Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
86
01:27Bioavailability Enhancement: Drug Permeability Enhancement
86
Body:After oral administration, poor permeability often limits the rate at which drugs are absorbed through the intestinal epithelium. Enhancing drug permeability is crucial for effective therapy, and several strategies have been developed to overcome this challenge.One effective strategy involves the use of lipid-based formulations. These formulations enhance dissolution and solubility, targeting physiological mechanisms to increase drug absorption. This includes stimulating bile salt...
86
01:16Therapeutic Drug Monitoring: Overview and Classification
106
Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood at designated intervals to ensure the drug concentration stays within a therapeutic range. This monitoring is crucial for optimizing individual dosage regimens, enhancing therapeutic efficacy, and minimizing drug-related toxicity. TDM is vital for drugs with narrow therapeutic windows, significant variability in pharmacokinetics, and a clear correlation between plasma levels and...
106
01:28Dosage Regimens: Designs and Approaches
123
Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
123
01:22Bioavailability Enhancement: Determination and Conceptual Approaches in Overcoming Bioavailability Problems
64
Body:Bioavailability is a critical pharmacological concept that measures the extent and rate at which an active drug ingredient or therapeutic moiety enters the systemic circulation, remaining unchanged. It's a pivotal factor in determining a drug's efficacy and safety.The Biopharmaceutics Classification System (BCS) plays an essential role in drug development by categorizing drugs into four classes based on their solubility and permeability. This classification aids in understanding drug...
64