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Lung cancer presenting as an acute appendicitis.
Jack Callum1,2, Julie Paik1, Michael Hibbert1,3
1Respiratory Department Royal North Shore Hospital Sydney NSW Australia.
Respirology Case Reports
|January 29, 2021
Summary
Appendiceal metastasis from lung cancer is rare, presenting as appendicitis. This case highlights lung adenocarcinoma spreading to the appendix, emphasizing diverse metastatic lung cancer presentations.
Area of Science:
- Oncology
- Gastroenterology
- Pathology
Background:
- Appendiceal metastasis from primary lung cancer is an exceptionally rare clinical finding.
- Appendicitis is an uncommon presentation for metastatic lung disease.
Observation:
- A 62-year-old male presented with right lower quadrant pain, indicative of appendicitis.
- Diagnostic workup revealed a concurrent lung mass and mediastinal lymphadenopathy.
Findings:
- Histopathological examination confirmed lung adenocarcinoma.
- Immunohistochemistry of the appendiceal tissue showed a similar staining pattern for thyroid transcription factor 1 (TTF-1) and cytokeratin 7 (CK-7) as the lung tumor.
- A literature review identified 12 prior cases of lung metastasis to the appendix causing appendicitis.
Implications:
- This case underscores the varied clinical presentations of metastatic lung cancer.
- Appendicitis can be the initial symptom leading to the diagnosis of primary lung cancer.
- Recognizing rare metastatic patterns is crucial for accurate diagnosis and timely treatment of lung adenocarcinoma.
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