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Plasma-activated interfaces for biomedical engineering.

Pei Liu1, Guomin Wang1, Qingdong Ruan1

  • 1Department of Physics, Department of Materials Science and Engineering, and Department of Biomedical Engineering, City University of Hong Kong, Tat Chee Avenue, Kowloon, 999077, Hong Kong, China.

Bioactive Materials
|January 29, 2021
PubMed
Summary
This summary is machine-generated.

Plasma-activated surfaces create specific biomedical interfaces to control cell signaling for improved disease monitoring and therapeutic outcomes. This review guides researchers in selecting plasma conditions for optimal interface design and biological function.

Keywords:
Bioactive interfacesBiomedical engineeringPlasma-assisted processes

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Area of Science:

  • Biomedical Engineering
  • Surface Science
  • Plasma Physics

Background:

  • Cell signaling at interfaces is crucial for disease monitoring and therapeutic development.
  • Biomedical interfaces regulate information transmission for enhanced patient outcomes.
  • Plasma technology offers a versatile tool for constructing functional biomedical interfaces.

Purpose of the Study:

  • To review the current state of plasma-activated interfaces in biomedical applications.
  • To categorize plasma-activated interfaces based on their interaction with biological systems.
  • To provide guidance for selecting plasma processing conditions for optimal interface design.

Main Methods:

  • Review of existing literature on plasma-activated surfaces in biomedicine.
  • Categorization of interfaces into direct (plasma-cell) and indirect (plasma-material-cell) types.
  • Analysis of plasma processing parameters and their impact on interface function.

Main Results:

  • Plasma-activated surfaces demonstrate potent functions in bacteria inactivation, tissue regeneration, and cancer therapy.
  • Categorization provides a framework for understanding different plasma-interface-biology interactions.
  • Guidance is offered for tailoring plasma treatments to specific biomedical needs.

Conclusions:

  • Plasma-activated interfaces represent a significant advancement in biomedical engineering.
  • Further interdisciplinary research is needed to expedite clinical applications.
  • Optimized plasma processing is key to unlocking the full therapeutic potential of these interfaces.