[Differential diagnosis of pathogenetic types of cerebral ischemic infarctions]

P A Machinsky1, N A Plotnikova2, V E Ulyankin1

  • 1N.P. Ogarev Mordovia National Research State University, Saransk, Russia.

Arkhiv Patologii
|January 29, 2021
PubMed

Insights

This review differentiates pathogenetic types of cerebral infarction, highlighting features of ischemic strokes in cerebrovascular diseases and other conditions. It identifies key morphological components for accurate diagnosis.

Area of Science:

  • Neurology
  • Pathology
  • Internal Medicine

Background:

  • Cerebral infarction diagnosis requires differentiating various pathogenetic types.
  • Ischemic strokes present features overlapping with cerebrovascular diseases and other systemic conditions.
  • Accurate differential diagnosis is crucial for effective patient management.

Purpose of the Study:

  • To conduct a literature review on the differential diagnosis of pathogenetic types of cerebral infarction.
  • To identify characteristic features of ischemic strokes in cerebrovascular diseases and other nosological entities.
  • To analyze leading morphological components for classifying cerebral infarctions.

Main Methods:

  • Literature review of differential diagnosis for cerebral infarction.
  • Analysis of morphological components associated with ischemic stroke subtypes.
  • Comparison of features across cerebrovascular and non-cerebrovascular causes of stroke.

Main Results:

  • Identified distinct morphological components for atherothrombotic, cardioembolic, lacunar, hemodynamic, and hemorheological cerebral infarctions.
  • Highlighted overlapping and unique features of ischemic strokes in systemic diseases (e.g., tumors, blood, heart, liver, kidney disorders).
  • Established a basis for differentiating pathogenetic types of cerebral infarction.

Conclusions:

  • Differential diagnosis of cerebral infarction involves recognizing specific morphological patterns.
  • Understanding features associated with both primary cerebrovascular and secondary causes is essential.
  • This review aids in distinguishing the pathogenetic origins of acute ischemic stroke.

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