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Updated: Nov 19, 2025

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice
Published on: November 27, 2019
Time-Restricted Eating, Intermittent Fasting, and Fasting-Mimicking Diets in Weight Loss
Maura Fanti1, Amrendra Mishra1, Valter D Longo1,2
1Longevity Institute and Davis School of Gerontology, University of Southern California, Los Angeles, CA, 90089, USA.
Purpose Of Review:
This article reviews the current literature on dietary interventions, including time-restricted eating (TRE), intermittent fasting (IF), and fasting-mimicking diets (FMD) and their effects on weight loss.
Recent Findings:
Dietary interventions, primarily known for their potential health benefits, are attracting considerable interest also for their effects on weight loss. The literature suggests that many popular diets can induce weight loss but only a limited number of studies actually demonstrate long-term weight loss efficacy. Here we present an update on the latest studies on some of the most popular dietary interventions able to trigger the physiology of fasting and highlight their impact on weight loss in overweight or obese individuals.
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