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Women and COVID-19: severity and mortality in hospitalized middle-aged and older patients
L Balcázar-Hernández1,2,3, C Martínez-Murillo1, C Ramos-Peñafiel1,4,5
1Hematology Department, Hospital General de México, Mexico City, Mexico.
Objective:
The aim of the study was to evaluate the clinical features, severity, and mortality of coronavirus disease-2019 (COVID-19) in hospitalized middle-aged and older women, and the risk factors associated with severity and mortality in women.
Methods:
A retrospective study was conducted in hospitalized patients with COVID-19. The clinical features, severity, and mortality of COVID-19 in middle-aged and older women (age 45 years and older) were compared to those of younger women (age <45 years).
Results:
A higher frequency of hypertension, invasive mechanical ventilation (IMV) requirement, and mortality was evidenced in middle-aged and older women. Age ≥45 years (odds ratio 2.7; 95% confidence interval 1.21-6.27; p = 0.01) and IMV requirement (odds ratio 3.0; 95% confidence interval 1.34-6.76; p = 0.004) predicted mortality.
Conclusions:
Severity and mortality are higher in middle-aged and older women with COVID-19 compared to younger women.
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