Related Experiment Video
Updated: Nov 19, 2025

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
Published on: June 27, 2025
Is it Possible to Predict Massive Bleeding in Nulliparous Women with Placenta Previa?
Gokcen Orgul1, Sule Goncu Ayhan1, Gulhan Cetinkaya Saracoglu1
1Department of Perinatology, University of Health Sciences, Ankara, Turkey.
Objective:
We evaluated risk factors to determine if there were specific risk factors that could predict massive bleeding in nulliparous women with placenta previa.
Methods:
The participants were classified into two groups. Women with a calculated blood loss ≥ 1,000 mL were included in the massive bleeding group. Women without any signs or symptoms related with hypovolemia or with a calculated bleeding volume < 1,000 mL were categorized into the non-massive bleeding group.
Results:
There were 28 patients (40.6%) with massive bleeding and 41 cases (59.4%) with non-massive bleeding. The calculated blood loss and number of cases that required red cell transfusions were statistically different between the groups (< 0.005 and 0.002, respectively). There were no statistically significant differences in terms of maternal or fetal factors, placental location, or delivery characteristics between the two groups.
Conclusion:
We could not determine the predictive features for massive hemorrhage based on clinical features, delivery features, or placental location.
Related Concept Videos
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Formation of the Platelet Plug
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Venous Thrombosis IV: Nursing Management
Mitral Valve Prolapse III: Nursing Management

