Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Calculation of the inbreeding coefficient.

W Boucher1

  • 1Enrico Fermi Institute, University of Chicago, IL 60637.

Journal of Mathematical Biology
|January 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Publisher Correction: Live-cell three-dimensional single-molecule tracking reveals modulation of enhancer dynamics by NuRD.

Nature structural & molecular biology·2023
Same author

Live-cell three-dimensional single-molecule tracking reveals modulation of enhancer dynamics by NuRD.

Nature structural & molecular biology·2023
Same author

Luteolin inhibits myelin basic protein-induced human mast cell activation and mast cell-dependent stimulation of Jurkat T cells.

British journal of pharmacology·2008
Same author

Intravesical nanocrystalline silver decreases experimental bladder inflammation.

The Journal of urology·2008
Same author

The flavonoid luteolin inhibits niacin-induced flush.

British journal of pharmacology·2008
Same author

Anti-chemokine therapy for inflammatory diseases.

International journal of immunopathology and pharmacology·2007
Same journal

Dynamic resource allocation in eukaryotic Resource Balance Analysis.

Journal of mathematical biology·2026
Same journal

Discrete-time exploitative competition model of different stage-specific predators.

Journal of mathematical biology·2026
Same journal

Spatiotemporal SEIQR Epidemic Modeling with Optimal Control for Vaccination, Treatment, and Social Measures.

Journal of mathematical biology·2026
Same journal

Phenotypic plasticity trade-offs in an age-structured model of bacterial growth under stress.

Journal of mathematical biology·2026
Same journal

Intraspecific interactions facilitate mutualism across multilayer networks under weak selection.

Journal of mathematical biology·2026
Same journal

A two-species competition model on a compact metric graph for the invasion and competition of Aedes Aegypti and Aedes Albopictus mosquitoes in Florida.

Journal of mathematical biology·2026
See all related articles

Wright's rule provides a method for calculating the inbreeding coefficient in genetic pedigrees. This study proves the rule's validity for both autosomal and X-linked genetic loci.

Area of Science:

  • Genetics
  • Quantitative Genetics
  • Population Genetics

Background:

  • Inbreeding, the mating of related individuals, increases homozygosity.
  • The inbreeding coefficient (F) quantifies the probability that an individual inherits identical alleles from both parents.
  • Calculating F for complex pedigrees is crucial in genetic studies.

Purpose of the Study:

  • To provide a formal proof for Wright's rule in calculating the inbreeding coefficient.
  • To demonstrate the applicability of Wright's rule across different inheritance patterns.

Main Methods:

  • Mathematical derivation and proof of Wright's rule.
  • Application of the rule to autosomal and X-linked genetic loci.

Main Results:

Related Experiment Videos

  • Wright's rule is mathematically proven to be accurate for calculating the inbreeding coefficient.
  • The rule's validity is confirmed for both autosomal and X-linked inheritance patterns.

Conclusions:

  • Wright's rule is a robust and universally applicable method for determining the inbreeding coefficient.
  • The findings support the use of Wright's rule in diverse genetic analyses involving pedigrees.