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Updated: Nov 19, 2025

Quantitative Visualization and Detection of Skin Cancer Using Dynamic Thermal Imaging
Published on: May 5, 2011
Contact, high-resolution spatial diffuse reflectance imaging system for skin condition diagnosis: a first-in-human
Anne Koenig1, Nils Petitdidier1,2, Henri Grateau1
1Université Grenoble Alpes, France-CEA, LETI, MINATEC Campus, Grenoble, France.
Significance:
Oxygenation is one of the skin tissue physiological properties to follow for patient care management. Furthermore, long-term monitoring of such parameters is needed at the patient bed as well as outside the hospital. Diffuse reflectance spectroscopy has been widely used for this purpose.
Aim:
The aim of the study is to propose a low-cost system for the long-term measurement of skin physiological parameters in contact.
Approach:
We have developed a low-cost, wearable, CMOS-based device. We propose an original method for processing diffuse reflectance data to calculate the tissue oxygen saturation (StO2).
Results:
We tested the device for the assessment of tissue oxygenation during a first-in-human clinical trial that took place at the Grenoble University Hospital France.
Conclusions:
The results of this clinical trial show a good accordance between our sensor and commercial devices used a reference.

