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Comparing the effect of PCV10 and PCV13 paediatric vaccination programmes
Christian Theilacker1, Mark A Fletcher2, Julia R Spinardi3
1Pfizer Deutschland GmbH, 10785 Berlin, Germany.
The Lancet. Infectious Diseases
|January 30, 2021
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Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
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