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Updated: Nov 19, 2025

Simultaneous Brightfield, Fluorescence, and Optical Coherence Tomographic Imaging of Contracting Cardiac Trabeculae Ex Vivo
Published on: October 2, 2021
Multi-beam OCT imaging based on an integrated, free-space interferometer
Yongjoo Kim1,2, Norman Lippok1,2, Benjamin J Vakoc1,2,3
1Wellman Center for Photomedicine, Massachusetts General Hospital, 40 Blossom St., Boston, MA 02114, USA.
Abstract:
While it is a common practice to increase the speed of swept-source optical coherence tomography (OCT) systems by using a high-speed source, this approach may not always be optimal. Parallelization in the form of multiple imaging beams is an alternative approach, but scalable and low-loss multi-beam OCT architectures are needed to capitalize on its advantages. In this study, we demonstrate an eight-beam OCT system using an interferometer architecture comprising planar lightwave circuits (PLC) splitters, V-groove assemblies (VGA), and optical ribbon fibers. We achieved an excess loss and heterodyne efficiency on each channel that was close to that of single-beam systems. In vivo structural imaging of a human finger and OCT angiography imaging of a mouse ear was performed to demonstrate the imaging performance of the system. This work provides further evidence supporting multi-beam architectures as a viable strategy for increasing OCT imaging speed.
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