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Meralgia Paresthetica Successfully Treated with Palmithoylethanolamide.

Rocco Salvatore Calabrò^1,2,3,4, Carmela Casella^1,2,3,4, Alfredo Manuli^1,2,3,4

¹Drs. Calabrò and Manuli are with IRCCS Centro Neurolesi "Bonino Pulejo" in Messina, Italy.

Innovations in Clinical Neuroscience

|February 1, 2021

Summary

Palmitoylethanolamide (PEA) effectively treated a patient with meralgia paresthetica (MP), a nerve entrapment condition. This suggests PEA may be a viable non-surgical option for peripheral neuropathies like MP.

Keywords:

Polyneuropathy inflammation nutraceuticals

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Area of Science:

Neurology
Pain Management
Pharmacology

Background:

Meralgia paresthetica (MP) is an uncommon entrapment mononeuropathy causing thigh numbness and paresthesia.
Palmitoylethanolamide (PEA) is recognized for its therapeutic effects in chronic pain and neuropathic conditions.

Observation:

A case study involved a 28-year-old patient experiencing posttraumatic MP for three months.
The patient was otherwise healthy, indicating MP as the primary condition.

Findings:

Successful treatment of MP was achieved using Palmitoylethanolamide (PEA) at a dosage of 1200mg/day.
The patient experienced symptom resolution, indicating PEA's efficacy in managing MP.

Implications:

PEA demonstrates potential as a therapeutic agent for peripheral neuropathies, including meralgia paresthetica.
Further research into PEA for neuropathies could lead to non-invasive treatment alternatives, potentially avoiding surgery.