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Updated: Nov 19, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
COVID-19 pandemic and transfusion medicine: the worldwide challenge and its implications
Layal Al Mahmasani1, Mohammad Hassan Hodroj1, Antoine Finianos2
1Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Insights
The COVID-19 pandemic challenged transfusion medicine, leading to blood shortages. Convalescent plasma emerged as a promising treatment for severe COVID-19 cases.
Area of Science:
- Transfusion Medicine
- Infectious Diseases
- Hematology
Background:
- The COVID-19 pandemic significantly impacted global transfusion medicine services.
- Emerging challenges included blood product shortages and concerns over blood product safety.
- The pandemic necessitated implementing measures to reduce blood demand and boost donations safely.
Purpose of the Study:
- To address the challenges in transfusion medicine during the COVID-19 pandemic.
- To explore the potential of plasma therapy for treating COVID-19 patients.
- To review strategies for maintaining blood supply and safety amidst the pandemic.
Main Methods:
- Review of implemented measures to manage blood supply and donation during the pandemic.
- Analysis of the proposed role and ongoing studies of plasma therapy for COVID-19.
- Exploration of alternative therapeutic options.
Main Results:
- Several countries successfully navigated transfusion medicine challenges during the pandemic.
- Convalescent plasma therapy is under investigation as a potential treatment for severe COVID-19.
- Ongoing research is evaluating the efficacy of plasma therapy and other treatments.
Conclusions:
- Transfusion medicine adapted to pandemic-related challenges through strategic interventions.
- Convalescent plasma shows promise as a rescue therapy for severe COVID-19.
- Continued research is vital for optimizing COVID-19 treatments and transfusion practices.
Abstract:
COVID-19 pandemic has imposed worldwide challenge and has significantly affected transfusion medicine. Shortage in blood products along with concerns regarding the safety of blood products have emerged. Measures to overcome these challenges have been implemented in order to decrease the demand on blood products and to encourage blood donations while taking full precautions to minimize risk of COVID-19 transmission mainly at blood banks and medical centers. Several countries have been successful in facing these new challenges. In addition, the role of plasma therapy in the treatment of COVID-19 patients, especially in severe cases, has been proposed and current studies are being conducted to determine its efficacy. Other therapeutic options are currently being explored. So far, the use of convalescent plasma is considered a promising rescue treatment to be looked at.
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