Restless sleep disorder, restless legs syndrome, and periodic limb movement disorder-Sleep in motion!

Lourdes M DelRosso1, Maria P Mogavero2, Raffaele Ferri3

  • 1Seattle Children's Hospital, Seattle, Washington, USA.

Pediatric Pulmonology
|February 2, 2021
PubMed

Insights

Pediatric sleep disorders like restless sleep disorder (RSD), restless legs syndrome (RLS), and periodic limb movements of sleep disorder (PLMD) disrupt sleep. Research is advancing to better understand and diagnose these conditions in children.

Area of Science:

  • Pediatric Sleep Medicine
  • Neurology
  • Movement Disorders

Background:

  • Sleep-related movement disorders (SRMDs) are common in children, often presenting as restless sleep.
  • Restless sleep affects up to 80% of children with restless legs syndrome (RLS) and periodic limb movements of sleep disorder (PLMD).
  • Restless Sleep Disorder (RSD) is a newly identified primary pediatric sleep disorder characterized by restless sleep and associated daytime consequences.

Purpose of the Study:

  • To describe three main pediatric SRMDs: RSD, RLS, and PLMD.
  • To explain the new consensus criteria for diagnosing RSD.
  • To highlight research advancements and propose future research directions in pediatric SRMD.

Main Methods:

  • Review of published data on pediatric SRMDs.
  • Analysis of phenomenology and consequences of sleep-related movements in children.
  • Discussion of new diagnostic approaches and guidelines.

Main Results:

  • Sleep-related movements significantly disrupt sleep quality and continuity in children.
  • While research in adults is advancing, pediatric SRMD research is in its early stages.
  • Convincing evidence links sleep-related movements to disrupted sleep.

Conclusions:

  • Pediatric SRMDs, including RSD, RLS, and PLMD, require further investigation.
  • Standardized diagnostic methods and specific guidelines are needed for pediatric SRMD.
  • Future research should focus on the detailed analysis of sleep-related movements in children.

Related Concept Videos

Restless Leg Syndrome and Night Terrors01:27

Restless Leg Syndrome and Night Terrors

Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
328
REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
857
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
2.3K
Sleepwalking and Sleep Talking01:17

Sleepwalking and Sleep Talking

Somnambulism, commonly known as sleepwalking, involves individuals engaging in activities ranging from simple walking to more complex behaviors such as driving. Sleepwalking typically occurs during the slow-wave sleep stages 3 and 4 early in the night when the person is not dreaming, contradicting the myth that sleepwalkers are acting out their dreams.
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
484
Narcolepsy01:07

Narcolepsy

Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
298
Stages of Sleep01:22

Stages of Sleep

Sleep progresses through distinct stages, each characterized by specific brain wave patterns and physiological responses ranging from wakefulness to stages of non-rapid eye movement, known as non-REM, to rapid eye movement, referred to as REM. Understanding these stages helps in recognizing how sleep supports various bodily and cognitive functions.
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...
1.0K