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Updated: Nov 19, 2025

Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization
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The Role of TEG Analysis in Patients with COVID-19-Associated Coagulopathy: A Systematic Review

Jan Hartmann1, Alexis Ergang1, Dan Mason1

  • 1Haemonetics Corporation, Boston, MA 02110, USA.

Diagnostics (Basel, Switzerland)
|February 3, 2021
PubMed

Insights

Thromboelastography effectively identifies hypercoagulability in COVID-19 patients and predicts thrombotic risks. This whole blood test offers advantages over traditional lab tests for managing COVID-19-associated coagulopathy.

Area of Science:

  • Hematology
  • Critical Care Medicine
  • Diagnostic Technologies

Background:

  • COVID-19-associated coagulopathy (CAC) presents a hypercoagulable state with increased thrombotic risk.
  • Standard diagnostic and management protocols for CAC are not yet established.
  • Whole blood viscoelastic tests offer a comprehensive assessment of coagulation status.

Purpose of the Study:

  • To systematically review the utility of thromboelastography (TEG) in managing patients with COVID-19.
  • To evaluate TEG's ability to identify hypercoagulable states and predict thrombotic complications in COVID-19 patients.

Main Methods:

  • Systematic literature review of MEDLINE (PubMed) and Cochrane databases.
  • Extraction and analysis of TEG parameter measurements and clinical outcomes from 15 publications.
  • Comparison of TEG benefits against traditional laboratory coagulation tests.

Main Results:

  • Thromboelastography can identify and assess hypercoagulability in COVID-19 patients.
  • TEG utilization in this population predicts thrombotic complications.
  • TEG offers advantages over standard laboratory coagulation tests for CAC diagnosis.

Conclusions:

  • Thromboelastography is a valuable tool for optimizing the diagnosis of COVID-19-associated coagulopathy.
  • TEG can improve patient management strategies for COVID-19.
  • Further research will elucidate optimal TEG applications in COVID-19 patient care.

Keywords:
COVID-19TEGblood coagulationcoronavirusfibrinolysisthromboelastographyviscoelastic

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