Related Experiment Video
Updated: Nov 18, 2025

A Pre-Clinical Porcine Model of Orthotopic Heart Transplantation
Published on: April 27, 2019
Post-Heart Transplant Care Pathway's Impact on Reducing Length of Stay
Lisa Guertin1, Melinda Earle, Todd Dardas
1University of Washington Medical Center, Seattle (Ms Guertin and Dr Dardas); Rush University College of Nursing, Chicago, Illinois (Dr Earle); and Decision Patterns, Oakland, California (Dr Brown).
Background:
Prolonged length of stay (LOS) has undesirable consequences including increased cost, resource consumption, morbidity, and disruptions in hospital flow.
Local Problem:
A high-volume heart transplant center in the Pacific Northwest had a mean index hospital LOS of 23 days, with a goal of 10 days according to the institutional heart transplant care pathway.
Methods:
A retrospective, regression analysis was used to identify the factors contributing to LOS of 41 post-heart transplant patients.
Interventions:
The post-heart transplant care pathway and order set were modified accordingly and reintroduced to the health care team.
Results:
Factors contributing to LOS included number of days (1) until the first therapeutic calcineurin inhibitor level, (2) until intravenous diuretics were no longer required, and (3) outside of a therapeutic calcineurin inhibitor range. The interventions reduced the mean LOS by 8 days.
Conclusions:
Increased awareness of LOS, education, and consistent use of care pathways can significantly reduce length of stay.
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