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Functional Fecal Incontinence in Children: Epidemiology, Pathophysiology, Evaluation, and Management
Shaman Rajindrajith1, Niranga Manjuri Devanarayana2, Nikhil Thapar3
1Department of Pediatrics, Faculty of Medicine, University of Colombo, Colombo 8.
Insights
Functional fecal incontinence (FI) affects children globally, impacting their quality of life. Diagnosis often relies on clinical history and Rome IV criteria, with varied treatments for constipation-associated and nonretentive FI.
Area of Science:
- Pediatric Gastroenterology
- Child Psychology
Background:
- Functional fecal incontinence (FI) is a common pediatric issue with significant psychological and quality-of-life impacts.
- FI presents as either constipation-associated FI or nonretentive FI, regardless of the underlying pathophysiology.
Purpose of the Study:
- To review the diagnosis and management of functional fecal incontinence in children.
- To highlight the importance of Rome IV criteria and evolving diagnostic tools.
Main Methods:
- Clinical history and physical examination using Rome IV criteria.
- Review of evolving diagnostic investigations like high-resolution anorectal and colonic manometry.
- Analysis of treatment strategies for different types of functional FI.
Main Results:
- Rome IV criteria and clinical assessment are typically sufficient for diagnosing functional FI.
- High-resolution manometry provides insights into the pathophysiology of functional FI.
- Conventional treatments are effective for most constipation-associated FI, while nonretentive FI requires psychologically based approaches.
Conclusions:
- Functional FI significantly affects children's well-being and requires tailored therapeutic options.
- While constipation-associated FI often responds to standard interventions, nonretentive FI necessitates specialized psychological support.
- Advanced interventions like botulinum toxin, transanal irrigation, and surgery may be considered for refractory cases.
Abstract:
Functional fecal incontinence (FI) is a worldwide problem in children and comprises constipation-associated FI and nonretentive FI. Irrespective of pathophysiology, both disorders impact negatively on the psychological well-being and quality of life of affected children. A thorough clinical history and physical examination using the Rome IV criteria are usually sufficient to diagnose these conditions in most children. Evolving investigations such as high-resolution anorectal and colonic manometry have shed new light on the pathophysiology of functional FI. Although conventional interventions such as toilet training and laxatives successfully treat most children with constipation-associated FI, children with nonretentive FI need more psychologically based therapeutic options. Intrasphincteric injection of botulinum toxin, transanal irrigation and, in select cases, surgical interventions have been used in more resistant children with constipation-associated FI.
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