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G-Protein-Coupled Receptor and Ion Channel Genes Used by Influenza Virus for Replication

Nichole Orr-Burks1, Jackelyn Murray1, Kyle V Todd1

  • 1Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA.

Journal of Virology
|February 4, 2021
PubMed
Summary

RNA interference screens identified host genes, including G-protein-coupled receptors (GPCRs) and ion channels, essential for influenza virus replication. Targeting these pro-influenza genes offers new host-directed antiviral strategies against influenza infection.

Keywords:
influenzasiRNAvirologyvirus-host interactions

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