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Published on: April 1, 2014
Meningitis caused by Streptococcus suis in humans
1Netherlands Reference Laboratory for Bacterial Meningitis, Academic Medical Center, Amsterdam.
Abstract:
Between 1968 and 1984, 30 strains of Streptococcus suis causing meningitis were isolated in the Netherlands. Twenty-eight strains were type 2, one was type 4, and one was untypable. The average age of the patients infected with these strains was 49 years (range, 21-76 years); the male-to-female ratio was 6.5. Twenty-five patients (83%) were employed in the pork industry. Two patients (7%) died. In seven cases (23%), predisposing factors were identified. The most frequent sequela was hearing loss (54% of surviving patients). The data for these 30 patients were compared with those for 30 patients from outside the Netherlands whose cases of meningitis due to S. suis type 2 were described between 1968 and 1985. No differences were found. The estimated annual risk of developing S. suis meningitis among Dutch abattoir workers and pig breeders was approximately 3.0/100,000--a rate 1,500 times higher than that among persons not working in the pork industry.
Insights
Streptococcus suis meningitis primarily affects pork industry workers, with type 2 being most common. Hearing loss is a frequent complication in survivors of this serious bacterial infection.
Area of Science:
- Infectious Diseases
- Bacteriology
- Epidemiology
Background:
- Streptococcus suis is an emerging zoonotic pathogen.
- Meningitis is a severe manifestation of Streptococcus suis infection.
- The epidemiology of Streptococcus suis meningitis in the pork industry requires further investigation.
Purpose of the Study:
- To describe the clinical characteristics and epidemiology of Streptococcus suis meningitis in the Netherlands.
- To compare Dutch cases with international data.
- To estimate the risk of Streptococcus suis meningitis in pork industry workers.
Main Methods:
- Retrospective analysis of 30 Streptococcus suis meningitis cases in the Netherlands (1968-1984).
- Comparison with 30 international cases of Streptococcus suis type 2 meningitis (1968-1985).
- Calculation of annual incidence rates for pork industry workers.
Main Results:
- Twenty-eight of 30 Dutch strains were Streptococcus suis type 2.
- Most patients (83%) worked in the pork industry, with an average age of 49.
- Hearing loss was the most common sequela (54% of survivors); mortality was 7%.
Conclusions:
- Streptococcus suis meningitis predominantly affects adult males in the pork industry.
- The risk for Dutch abattoir workers and pig breeders is significantly elevated (approx. 3.0/100,000 annually).
- Early recognition and preventative measures are crucial for this occupational hazard.
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