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Body:After oral administration, poor permeability often limits the rate at which drugs are absorbed through the intestinal epithelium. Enhancing drug permeability is crucial for effective therapy, and several strategies have been developed to overcome this challenge.One effective strategy involves the use of lipid-based formulations. These formulations enhance dissolution and solubility, targeting physiological mechanisms to increase drug absorption. This includes stimulating bile salt...

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Updated: Nov 18, 2025

Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins

Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins

Published on: August 31, 2019

Liposomes: Biomedical Applications.

Eun-Mi Kim¹, Hwan-Jeong Jeong¹

¹Department of Nuclear Medicine, Molecular Imaging & Therapeutic Medicine Research Center, Research Institute of Clinical Medicine of Jeonbuk National University and Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Korea.

Chonnam Medical Journal

|February 4, 2021

Summary

This summary is machine-generated.

Liposomes are versatile drug delivery systems that improve therapeutic efficacy and reduce toxicity. Future applications in diagnosis and theranostics are promising, despite remaining biological and translational challenges.

Keywords:

Drug Delivery Systems Liposomes Neoplasms Precision Medicine

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Area of Science:

Biomedical Engineering
Nanotechnology
Pharmacology

Background:

Liposomes offer flexible physicochemical and biophysical properties for drug delivery.
They overcome conventional therapy limitations by encapsulating agents, improving biodistribution and reducing toxicity.

Purpose of the Study:

To review liposomal formulation applications in biomedicine, focusing on therapy.
To discuss the future role of liposomes with advancements in diagnosis and theranostics.

Main Methods:

Literature review of liposomal formulation and applications.
Discussion of new techniques in imaging, targeting, and understanding tumor microenvironments.

Main Results:

Liposomes have been successfully applied as therapeutic agents.
Advancements in imaging, targeting, and theranostics are enhancing liposome potential.

Conclusions:

Liposomes are critical drug delivery systems with significant therapeutic potential.
Overcoming remaining biological and translational challenges is key for future clinical success.