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Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
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[The correlation between obstructive sleep apnea and olfaction function].

Yisong Jia1, Siying Lv1, Shangjie Bai1

  • 1Department of Otorhinolaryngology Head and Neck Surgery，Yanbian University Affiliated Hospital Organzation，Yanji，133000，China.

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Journal of Clinical Otorhinolaryngology Head and Neck Surgery
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Summary
This summary is machine-generated.

Obstructive sleep apnea (OSA) negatively impacts smell, with olfactory disorders increasing with OSA severity. This study highlights decreased olfactory cognition as a key symptom in OSA patients.

Keywords:
olfactory functionsleep apnea, obstructive

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Area of Science:

  • Neurology
  • Otorhinolaryngology
  • Sleep Medicine

Background:

  • Obstructive sleep apnea (OSA) is a prevalent sleep disorder.
  • Olfactory dysfunction is increasingly recognized as a comorbidity in various medical conditions.

Purpose of the Study:

  • To investigate olfactory function in untreated patients with obstructive sleep apnea (OSA).
  • To establish a reference for clinical olfactory research in OSA patients.

Main Methods:

  • 131 participants underwent overnight polysomnography (PSG) to categorize into OSA and non-OSA groups.
  • Olfactory function was assessed using the Korean version of the Sniffin' Sticks Test II (KVSS Test II).
  • Data analysis was performed using SPSS 26.0.

Main Results:

  • A significantly higher incidence of olfactory disorders was observed in the OSA group compared to the control group (P=0.001).
  • Olfactory disorder rates increased with OSA severity (P<0.05), particularly in severe OSA cases.
  • While overall olfactory scores showed no difference, OSA patients exhibited significantly lower olfactory threshold and cognitive scores (P<0.001).

Conclusions:

  • Obstructive sleep apnea (OSA) adversely affects olfactory function.
  • The severity of OSA is positively correlated with the incidence of olfactory disorders.
  • Olfactory dysfunction in OSA primarily manifests as reduced olfactory cognition and threshold.