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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
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Streptococcus salivarius endogenous endophthalmitis.
Carl-Joe Mehanna1, Lea Kallassi1, Ahmad M Mansour1
1Ophthalmology, American University of Beirut Medical Center, Hamra, Lebanon.
BMJ Case Reports
|February 5, 2021
Summary
This case study reports the first instance of endogenous endophthalmitis caused by Streptococcus salivarius in an elderly male patient. Prompt diagnosis and treatment are crucial for managing this rare opportunistic infection in individuals with comorbidities.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Endogenous endophthalmitis is a serious intraocular infection often associated with systemic conditions.
- Streptococcus salivarius is a common oral commensal, rarely implicated in severe endogenous infections.
Observation:
- An 88-year-old male with diabetes, iron deficiency anemia, and a history of transcatheter aortic valve implantation presented with atraumatic endophthalmitis.
- Despite a thorough investigation, no clear source of infection was identified.
- Ophthalmic examination revealed a papillomacular abscess.
Findings:
- Diagnostic and therapeutic vitrectomy was performed.
- Vitreous fluid cultures isolated Streptococcus salivarius.
- This represents the first reported case of endogenous endophthalmitis caused by S. salivarius.
Implications:
- Highlights the importance of considering atypical pathogens in immunocompromised patients with comorbidities.
- Emphasizes the need for high clinical suspicion for opportunistic infections.
- Underscores the critical role of early detection, microbiological evaluation, and prompt treatment in preventing severe visual outcomes.
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