Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Longitudinal Studies01:26

Longitudinal Studies

338
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
338
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

265
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
265
Strategies for Assessing and Addressing Confounding01:25

Strategies for Assessing and Addressing Confounding

221
Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
221
Introduction To Survival Analysis01:18

Introduction To Survival Analysis

513
Survival analysis is a statistical method used to study time-to-event data, where the "event" might represent outcomes like death, disease relapse, system failure, or recovery. A unique feature of survival data is censoring, which occurs when the event of interest has not been observed for some individuals during the study period. This requires specialized techniques to handle incomplete data effectively.
The primary goal of survival analysis is to estimate survival time—the time...
513

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Childhood Maltreatment and Adult Multimorbidity.

JAMA network open·2026
Same author

Associations between liking patterns for foods characterised by high/low fat content and sweet/savoury profiles and health outcomes: findings from the UK Biobank prospective cohort study.

The British journal of nutrition·2026
Same author

Comparative effectiveness and safety of pharmacological interventions for sleep outcomes in chronic non-cancer pain: a systematic review and network meta-analysis.

Sleep medicine reviews·2026
Same author

Accelerometry-measured prolonged and interrupted sedentary behavior and cancer incidence and mortality: A cohort study of 91,292 UK Biobank participants.

PLoS medicine·2026
Same author

Safety of Biologic and Targeted Synthetic Disease-Modifying Antirheumatic Drugs in Rheumatoid Arthritis: A Longitudinal Analysis.

Drug safety·2026
Same author

Cardiovascular outcomes and safety associated with statin therapy for primary prevention in older adults with type 2 diabetes: A target trial emulation study.

PLoS medicine·2026

Related Experiment Video

Updated: Nov 18, 2025

A Multi-Modal Approach to Assessing Recovery in Youth Athletes Following Concussion
10:31

A Multi-Modal Approach to Assessing Recovery in Youth Athletes Following Concussion

Published on: September 25, 2014

13.7K

Quantification of injury burden using multiple data sources: a longitudinal study.

Keith T S Tung1, Frederick K Ho1,2, Wilfred H S Wong1

  • 1Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, University of Hong Kong, Room 123, New Clinical Building, Pok Fu Lam, Hong Kong, China.

Scientific Reports
|February 5, 2021
PubMed
Summary

This study developed Hong Kong-specific disability weights (DWs) using patient data and hospital records to quantify injury burden. Findings highlight the importance of diverse data sources for effective injury prevention strategies.

More Related Videos

A Coupled Experiment-finite Element Modeling Methodology for Assessing High Strain Rate Mechanical Response of Soft Biomaterials
11:28

A Coupled Experiment-finite Element Modeling Methodology for Assessing High Strain Rate Mechanical Response of Soft Biomaterials

Published on: May 18, 2015

12.7K
Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury
07:21

Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury

Published on: May 27, 2022

3.4K

Related Experiment Videos

Last Updated: Nov 18, 2025

A Multi-Modal Approach to Assessing Recovery in Youth Athletes Following Concussion
10:31

A Multi-Modal Approach to Assessing Recovery in Youth Athletes Following Concussion

Published on: September 25, 2014

13.7K
A Coupled Experiment-finite Element Modeling Methodology for Assessing High Strain Rate Mechanical Response of Soft Biomaterials
11:28

A Coupled Experiment-finite Element Modeling Methodology for Assessing High Strain Rate Mechanical Response of Soft Biomaterials

Published on: May 18, 2015

12.7K
Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury
07:21

Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury

Published on: May 27, 2022

3.4K

Area of Science:

  • Public Health
  • Epidemiology
  • Health Services Research

Background:

  • Quantifying injury burden is crucial for effective injury prevention and policy development.
  • Existing disability weights (DWs) may not accurately reflect local contexts.
  • Hong Kong lacked specific, patient-derived DWs for injury burden assessment.

Purpose of the Study:

  • To generate Hong Kong-specific disability weights (DWs) for injuries.
  • To estimate the burden of injury in Hong Kong using patient-reported outcomes and hospital data.
  • To compare Hong Kong's injury burden with international studies like UK Burden of Injury (UKBOI) and Global Burden of Diseases (GBD).

Main Methods:

  • Patient recruitment from three major trauma centers in Hong Kong (September 2014 - December 2015).
  • Health-related quality of life interviews with patients up to three times over a 12-month period.
  • Estimation of DWs using patient-reported data, combined with mortality and inpatient data (2001-2012).

Main Results:

  • A total of 22,856 mortality and 817,953 morbidity cases due to injuries were identified.
  • The injury burden in Hong Kong was calculated as 1,027,641 disability-adjusted life years (DALYs).
  • Hong Kong's DALYs per 100,000 (1192) were lower than UKBOI (2924) and GBD (3459) estimates.

Conclusions:

  • The study successfully generated Hong Kong-specific disability weights (DWs) for injuries.
  • Utilizing multiple data sources, including patient-reported data and hospital records, enhances the accuracy of injury burden estimation.
  • Findings provide valuable data for informing injury prevention policies and resource allocation in Hong Kong.