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Updated: Nov 18, 2025

A Preterm Rat Model for Pain Studies
Published on: February 9, 2024
Massage therapy for paediatric procedural pain: A rapid review
Kylie Bernstein1, Mohammad Karkhaneh1, Liliane Zorzela1
1Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta.
Background:
Pain is a common paediatric problem, and procedural pain, in particular, can be difficult to manage. Complementary therapies are often sought for pain management, including massage therapy (MT). We assessed the evidence for use of MT for acute procedural pain management in children.
Methods:
We searched five main databases for (i) primary studies in English, (ii) included children 0 to 18 years of age, (iii) compared MT for procedural pain management to standard care alone or placebo, and (iv) measured pain as the primary or secondary outcome. The data were extracted by one author and verified by a second author. Randomized controlled trials were evaluated using the Cochrane Risk of Bias tool.
Results:
Eleven paediatric trials of procedural pain in neonatal, burn, and oncology populations, a total of 771 participants, were identified. Eight reported statistically significant reductions in pain after MT compared to standard care. Pain was measured using validated pain scales, or physiologic indicators. The studies were heterogeneous in population, techniques, and outcome measures used. No adverse events associated with MT were identified.
Conclusion:
MT may be an effective nonpharmacologic adjunct for management of procedural pain in children.

