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Related Concept Videos

Assessment of the Mouth01:26

Assessment of the Mouth

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A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
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Updated: Nov 18, 2025

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients
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Oral lichen planus - case report.

Cristian Sebastian Vlad1, Daliborca Cristina Vlad, Roxana Popescu

  • 1Department of Cell and Molecular Biology, Department of Microbiology, Victor Babeş University of Medicine and Pharmacy, Timişoara, Romania; popescu.roxana@umft.ro, boruga.madalina1@gmail.com.

Romanian Journal of Morphology and Embryology = Revue Roumaine De Morphologie Et Embryologie
|February 5, 2021
PubMed
Summary
This summary is machine-generated.

This case study highlights oral lichen planus in a heavy smoker. Prompt diagnosis and treatment with corticosteroids and immunomodulators led to favorable clinical outcomes.

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Area of Science:

  • Oral pathology
  • Immunohistochemistry
  • Dermatology

Background:

  • Oral lichen planus (OLP) is a chronic inflammatory condition affecting oral mucosa.
  • Differential diagnosis of OLP can be challenging due to polymorphic oral lesions.
  • Heavy smoking is a potential risk factor for various oral conditions.

Observation:

  • A 58-year-old female heavy smoker presented with acute oral pain, mastication, and feeding difficulties.
  • Macroscopic examination revealed erosive lesions and ulcerations requiring differential diagnosis.
  • Immunohistochemical analysis assessed S100 protein, Ki67, CD4, CD8, and CD20 immune cell markers.

Findings:

  • Biopsy excluded oral erythroplakia and carcinoma.
  • Clinical and pathological assessment confirmed the diagnosis of oral lichen planus.
  • Immunohistochemistry provided insights into the immune cell infiltrate.

Implications:

  • Early and accurate diagnosis of oral lichen planus is crucial for effective management.
  • Corticosteroids and immunomodulatory agents are effective in treating oral lichen planus.
  • Understanding the role of immune markers can aid in OLP diagnosis and management.