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Updated: Nov 18, 2025

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Modern pulmonary imaging of bronchopulmonary dysplasia
Nara S Higano1,2, J Lauren Ruoss3, Jason C Woods4,5,6,7
1Center for Pulmonary Imaging Research, Division of Pulmonary Medicine and Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Insights
Bronchopulmonary dysplasia (BPD) in preterm infants is a serious condition with limited early prognostic indicators. Pulmonary imaging offers promising methods for early risk stratification and guiding treatment strategies for BPD.
Area of Science:
- Neonatal Medicine
- Pediatric Pulmonology
- Medical Imaging
Background:
- Bronchopulmonary dysplasia (BPD) is a significant cause of morbidity and mortality in preterm infants.
- Despite advances in neonatal care, BPD management remains challenging due to a lack of precise early prognostic indicators.
- The increasing survival of extremely preterm infants exacerbates the burden of BPD.
Purpose of the Study:
- To review cutting-edge pulmonary imaging research relevant to bronchopulmonary dysplasia (BPD).
- To discuss the translational value of novel imaging techniques in neonatal lung disease.
- To explore the potential of radiological modalities in early BPD risk stratification and treatment guidance.
Main Methods:
- Review of recent scientific literature on pulmonary imaging in neonatal populations.
- Analysis of findings from advanced imaging techniques with high translational potential.
- Discussion of the application of various radiological modalities at different stages of BPD.
Main Results:
- Recent pulmonary imaging research provides valuable insights into BPD pathogenesis and progression.
- Novel imaging methods show promise for identifying infants at risk of developing BPD.
- Imaging can potentially guide the timing and type of interventions for BPD.
Conclusions:
- Pulmonary imaging holds significant potential for improving the clinical management of BPD.
- Early risk stratification using imaging can lead to more precise and timely therapeutic strategies.
- Further research into the role of radiological modalities is crucial for optimizing BPD care.
Abstract:
Bronchopulmonary dysplasia (BPD) is a complex and serious cardiopulmonary morbidity in infants who are born preterm. Despite advances in clinical care, BPD remains a significant source of morbidity and mortality, due in large part to the increased survival of extremely preterm infants. There are few strong early prognostic indicators of BPD or its later outcomes, and evidence for the usage and timing of various interventions is minimal. As a result, clinical management is often imprecise. In this review, we highlight cutting-edge methods and findings from recent pulmonary imaging research that have high translational value. Further, we discuss the potential role that various radiological modalities may play in early risk stratification for development of BPD and in guiding treatment strategies of BPD when employed in varying severities and time-points throughout the neonatal disease course.
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