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Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
[New therapies in oncogeriatrics].
Djamel Ghebriou1, Coralie Prebet1, Guillaume Bonnet2
1Oncologie médicale, site Tenon, Institut universitaire de cancérologie, Assistance publique-Hôpitaux de Paris, Sorbonne université, unité de coordination et antennes d'oncogériatrie Île-de-France-Paris-Est, 20 rue de la Chine, 75020 Paris, France.
Cancer treatment adaptations are crucial for the heterogeneous elderly population. New evaluation criteria and advanced practice nurses in oncogeriatrics improve care for older cancer patients.
Area of Science:
- Geriatric Oncology
- Cancer Treatment Research
- Healthcare Innovation
Background:
- Cancer management is evolving rapidly, but current practices are not always suitable for the diverse elderly population.
- The intrinsic toxicity of anti-cancer treatments is often underestimated in older adults.
- Existing evaluations of cancer treatments in the elderly lack comprehensive criteria.
Purpose of the Study:
- To highlight the need for tailored cancer management strategies for elderly patients.
- To emphasize the importance of incorporating functional autonomy into treatment evaluations.
- To discuss the role of new data and healthcare professionals in improving oncogeriatric care.
Main Methods:
- Review of recent studies focusing on elderly cancer patients.
- Analysis of composite evaluation criteria combining efficacy and toxicity.
- Examination of organizational changes, including the integration of advanced practice nurses in oncogeriatrics.
Main Results:
- Recent studies utilize composite criteria that include functional autonomy loss.
- New organizational models are emerging to support elderly cancer care.
- There is a growing recognition of the heterogeneity within the elderly cancer population.
Conclusions:
- Current cancer treatment protocols require adaptation for elderly patients.
- Comprehensive evaluation criteria are essential for assessing treatment outcomes in older adults.
- Advanced practice nurses in oncogeriatrics are vital for future elderly cancer care.
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