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Molecular targeted treatment and drug delivery system for gastric cancer

Lanxin Jiang1,2, Xiaomin Gong1,3, Wangdi Liao1

  • 1Department of Gastroenterology, Key Laboratory of Digestive Diseases of Jiangxi Province, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.

Journal of Cancer Research and Clinical Oncology
|February 7, 2021
PubMed

Insights

New targeted therapies and drug delivery systems offer hope for improving gastric cancer treatment outcomes. This review highlights advances in molecular agents and delivery methods, focusing on drug carriers and targeting peptides for better gastric cancer management.

Area of Science:

  • Oncology
  • Gastroenterology
  • Pharmacology

Background:

  • Gastric cancer remains a significant global health challenge with low early diagnosis rates and poor treatment outcomes.
  • Most patients are diagnosed at advanced stages, necessitating effective drug treatments.
  • Current median overall survival for gastric cancer is low, highlighting the need for improved therapeutic strategies.

Purpose of the Study:

  • To review recent advancements in targeted therapy for gastric cancer.
  • To focus on novel molecular targeted agents and innovative drug delivery systems.
  • To emphasize the development of drug carriers and targeting peptides for enhanced gastric cancer management.

Main Methods:

  • Comprehensive literature review of targeted therapy in gastric cancer.
  • Analysis of novel molecular targeted therapeutic agents.
  • Evaluation of advancements in drug delivery systems, including drug carriers and targeting peptides.

Main Results:

  • Identification of emerging molecular targeted therapeutic agents for gastric cancer.
  • Detailed examination of new drug delivery systems, such as advanced drug carriers.
  • Highlighting the role of targeting peptides in improving drug delivery specificity and efficacy.

Conclusions:

  • Advances in molecular targeted agents and drug delivery systems are crucial for improving gastric cancer treatment.
  • Drug delivery systems, particularly drug carriers and targeting peptides, show significant promise.
  • Further development in these areas is essential for better gastric cancer management and patient survival.
Keywords:
Drug carriersDrug delivery systemsGastric cancerMolecular targeted therapyTargeted peptides

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