Microfluidic ratio metering devices fabricated in PMMA by CO2 laser
1NIBEC, Ulster University, Belfast, BT37 0QB Northern Ireland, UK.
Summary
This study details microfluidic fabrication using CO2 lasers on PMMA, creating U-shaped and V-shaped channels. These microfluidic devices are suitable for ocean sensing and biomedical applications.
Area of Science:
- Materials Science and Engineering
- Microfluidics and Lab-on-a-Chip Technology
- Laser-Based Manufacturing
Background:
- Microfluidic devices are crucial for various sensing applications, including environmental and biomedical fields.
- Efficient and precise fabrication methods are essential for developing advanced microfluidic systems.
- Polymethyl methacrylate (PMMA) is a common material for microfluidic device fabrication due to its optical clarity and machinability.
Purpose of the Study:
- To investigate and characterize microfluidic channel fabrication on cast PMMA using a 10.6 μm CO2 engraving laser.
- To compare the effects of raster and vector laser writing modes on channel geometry and surface properties.
- To explore post-fabrication treatments for channel smoothing and transparency enhancement.
Main Methods:
- Microfluidic channels were fabricated on cast PMMA using a CO2 laser in both raster and vector modes.
- Different focusing optics, including a 1.5″ lens and a High Power Density Focussing Optics lens, were employed.
- Channel cross-sections were analyzed using imaging and stylus profilometry. Post-fabrication treatments included heated IPA etching and chloroform vapor treatment.
Main Results:
- Raster laser writing produced U-shaped channels with a flatter base, while vector writing resulted in V-shaped channels.
- Channel steepness in vector mode increased with laser power; laser defocus allowed for broader, shallower channels.
- Heated IPA etching smoothed raster-engraved channels, and chloroform vapor treatment enhanced transparency. Bonding was achieved via chloroform vapor treatment.
Conclusions:
- CO2 laser engraving offers a versatile method for fabricating microfluidic devices in PMMA with controllable channel geometries.
- Post-fabrication treatments can significantly improve channel surface finish and optical properties.
- The fabricated microfluidic devices are suitable for applications such as dissolved CO2 analysis in ocean sensing and broader biomedical sensing platforms.


