COVID-19 with non-obstructive coronary artery disease in a young adult
Abu Baker Sheikh1, Zainab Ijaz2, Nismat Javed3
1Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM, USA.
Insights
Severe COVID-19 can cause heart attacks in young adults due to cytokine storms. This case highlights myocardial infarction in a young male with obesity and asthma, emphasizing inflammatory responses in acute coronary syndrome.
Area of Science:
- Cardiology
- Infectious Diseases
- Critical Care Medicine
Background:
- Severe COVID-19 is associated with a systemic inflammatory response, known as a cytokine storm.
- This inflammatory response can lead to severe complications, including acute myocardial infarction (AMI), even in younger individuals.
- The risk factors for AMI in the general population may not be present in these COVID-19 cases.
Abstract:
Systemic inflammatory response due to cytokine storm in severe COVID-19 cases can lead to acute myocardial infarction, also affecting the younger population, without significant risk factors. We present the case of a 36-year-old male with morbid obesity and well-controlled asthma who had developed COVID-19-induced acute respiratory distress syndrome requiring mechanical ventilation and, subsequently, extracorporeal membrane oxygenation (ECMO) who developed myocardial infarction on Day 10 of admission and died on Day 15 of admission due to sequelae of severe COVID-19 infection. In young patients with COVID-19-induced respiratory infection, severe inflammatory response can lead to acute coronary syndrome in absence of obstructive lesions or plaque ruptures.
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