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Pertussis in infants in Nordic countries

Amit Bhavsar1, Jussi Mertsola2, Anja Poulsen3

  • 1Epidemiology & Health Economics, GSK, Wavre, Belgium.

Acta Paediatrica (Oslo, Norway : 1992)
|February 8, 2021
PubMed

Insights

A life-course immunization strategy is crucial for pertussis control. Higher infant pertussis incidence in Denmark may stem from lacking adolescent booster vaccine recommendations, unlike other Nordic countries.

Area of Science:

  • Public Health
  • Epidemiology
  • Immunization Practices

Background:

  • Pertussis (whooping cough) remains a significant public health concern, particularly for infants.
  • Effective control requires a comprehensive life-course immunization approach.
  • Understanding pertussis incidence in relation to vaccination strategies is vital for Nordic countries.

Purpose of the Study:

  • To review pertussis incidence among infants in Denmark, Finland, Norway, and Sweden (2014-2018).
  • To analyze national surveillance systems and infant vaccination schedules.
  • To contextualize pertussis incidence within existing immunization policies.

Main Methods:

  • Collected data on pertussis incidence, vaccination schedules, and DTaP vaccine coverage (infancy).
  • Utilized publicly available data sources and expert opinions on national surveillance.
  • Compared vaccination schedules, including adolescent boosters and maternal immunization recommendations.

Main Results:

  • Infant vaccination schedules and DTaP vaccine coverage were similar across the four Nordic countries.
  • Denmark, Sweden, and Finland reported mean pertussis incidences of 168, 76, and 35 per 100,000 infant-years, respectively.
  • Adolescent booster recommendations were present in all countries except Denmark; maternal immunization was not recommended in any.

Conclusions:

  • The higher pertussis incidence in Denmark may be linked to the absence of adolescent booster vaccination recommendations.
  • National surveillance systems showed no systematic differences across the studied countries.
  • Further research is warranted to investigate the impact of adolescent boosters on pertussis control.
Abstract

Keywords:
InfantsNordic countriesTdaplife-course immunisationpertussis

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