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Diabetes-induced auditory complications: are they preventable? a comprehensive review of interventions
Fahimeh Hajiabolhassan1,2, Elham Tavanai3
1Department of Audiology, School of Rehabilitation, Tehran University of Medical Sciences, Pich-e-Shemiran, Enghelab Avenue, 0098, Tehran, Iran.
Abstract:
Diabetes mellitus is a chronic metabolic disorder characterized by elevated blood glucose levels, which, over time, lead to major chronic complications in various organs of the body. A growing body of research suggests that diabetes could also result in degenerative changes in the auditory system. To date, several attempts have been made to prevent and reduce diabetes-induced auditory complications. Such attempts have generally focused on disease modifying as well as other pharmacological treatments involving several herbal and non-herbal agents such as vitamins C and E, rutin, resveratrol, coffee, trigonelline, Dioscorea nipponica, red ginseng, Pterostilbene Bofutsushosan, Daisaikoto, tolrestat, ACE inhibitors (enalapril), Ca antagonists (nimodipine), Lipo-prostaglandin E1, methylprednisolone, dexamethasone, and chlorogenic acid and also other strategies like acupuncture. However, there is no consensus about which are the most effective strategies for preventing and reducing auditory complications in diabetic patients with few side effects and maximum efficacy. This paper provides a comprehensive review of interventions for preventing and treating diabetes-induced auditory complications to help therapists.
Insights
Diabetes can cause hearing loss. This review explores various treatments, including herbal remedies and medications, to prevent and manage diabetes-induced auditory complications effectively.
Area of Science:
- Otolaryngology
- Endocrinology
- Pharmacology
Background:
- Diabetes mellitus is a chronic metabolic disorder linked to widespread organ complications.
- Emerging evidence indicates a connection between diabetes and degenerative changes in the auditory system.
- Diabetic auditory complications represent a significant clinical challenge with limited consensus on management.
Purpose of the Study:
- To comprehensively review current interventions for preventing and treating diabetes-induced auditory complications.
- To evaluate the efficacy and side effect profiles of various therapeutic strategies.
- To provide guidance for clinicians managing auditory health in diabetic patients.
Main Methods:
- Systematic literature review of studies on interventions for diabetes-induced auditory complications.
- Analysis of pharmacological (herbal and non-herbal), and non-pharmacological strategies.
- Assessment of reported efficacy, side effects, and treatment consensus.
Main Results:
- A wide array of interventions, including vitamins C and E, resveratrol, and specific herbal agents, have been investigated.
- Pharmacological treatments like ACE inhibitors and acupuncture have also been explored.
- No single intervention has demonstrated clear superiority in efficacy and safety for all patients.
Conclusions:
- Effective strategies for preventing and treating diabetes-induced auditory complications remain under investigation.
- Further research is needed to establish consensus on optimal therapeutic approaches.
- Personalized treatment plans considering efficacy and side effects are crucial for diabetic patients with auditory issues.
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