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Gigantic amoebic liver abscess in pregnancy: A case report
K H Chiam1, Yvonne A L Lim2, Mahmud Rohela2
1Department of Internal Medicine, Hospital Keningau, Sabah, Malaysia.
Tropical Biomedicine
|February 9, 2021
Summary
Amoebic liver abscess during pregnancy is rare and difficult to diagnose due to subtle symptoms. Early detection, guided by elevated alkaline phosphatase and neutrophilia, is crucial for better outcomes in pregnant patients.
Area of Science:
- Medicine
- Hepatology
- Infectious Diseases
Background:
- Amoebic liver abscess (ALA) during pregnancy is a rare clinical presentation.
- Subtle and vague symptomatology often leads to diagnostic challenges and delayed diagnosis.
Purpose of the Study:
- To highlight the diagnostic challenges of ALA in pregnancy.
- To emphasize the importance of early diagnosis and a high index of suspicion.
Main Methods:
- Case report of a pregnant patient with ALA.
- Utilized a combination of biochemical, radiographic, and molecular investigations for diagnosis.
Main Results:
- Diagnosis was confirmed through integrated investigations.
- Elevated alkaline phosphatase and neutrophilia were consistent indicators of liver abscess in this case.
Conclusions:
- Early diagnosis of ALA in pregnancy is vital due to high maternal mortality risk.
- Clinicians should maintain a high index of suspicion, considering elevated alkaline phosphatase and neutrophilia as key indicators.
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