Normal head and neck lymph nodes in the paediatric population
J Alves Rosa1, J S Calle-Toro2, M Kidd3
1University Hospitals Bristol NHS Foundation Trust, UK; North Bristol NHS Trust, UK.
Clinical Radiology
|February 9, 2021
Summary
This study defines normal head and neck lymph node sizes in children. Larger, rounder lymph nodes can be normal findings in pediatric patients, varying by location and age.
Area of Science:
- Radiology
- Pediatric Imaging
- Head and Neck Anatomy
Background:
- Accurate assessment of pediatric head and neck lymph nodes is crucial for differentiating normal findings from pathology.
- Establishing normative data is essential for interpreting imaging studies in children.
Purpose of the Study:
- To establish the normal range of head and neck lymph node distribution, size, and shape in a pediatric population.
- To provide reference values for radiologists interpreting pediatric brain magnetic resonance imaging (MRI).
Main Methods:
- Retrospective review of 200 pediatric brain MRI examinations (age 5 months to 16 years).
- Exclusion of cases with potential causes of lymphadenopathy.
- Assessment of eight head and neck regions for lymph node presence, measurement of short and long axes, and calculation of the short/long axis ratio.
Main Results:
- Deep cervical, submandibular, and posterior cervical nodes were most commonly identified.
- Mean long axis measurements were largest for submandibular (19.7 mm), deep cervical (18.1 mm), and posterior cervical (15.4 mm) nodes.
- Pre-auricular, occipital, and submental nodes showed the most oval shapes (S/L ratio 0.64, 0.63, 0.6).
- A stronger positive correlation between occipital and deep cervical lymph node size and age was observed.
Conclusions:
- This study characterizes normal head and neck lymph node appearance in healthy children.
- Findings suggest that larger and rounder lymph nodes can be normal variants in pediatric patients.
- Age and anatomical location are important factors in interpreting lymph node morphology.
Related Concept Videos
Detailed Structure and Function of Lymph Nodes
3.6K
Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
3.6K
Secondary Lymphoid Organs
8.2K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
8.2K
Development of the Lymphatic System
1.6K
The development of lymphatic tissues and vessels in embryonic life begins around the fifth week. These structures originate from the mesoderm layer, with lymph sacs emerging from developing veins.
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
1.6K
Primary Lymphoid Organs
13.5K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
13.5K
Lymphoid Cells and Tissues
2.3K
Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
2.3K
Veins of Head and Neck
4.1K
The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
4.1K


