Related Experiment Video
Updated: Nov 18, 2025
Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns
Published on: May 12, 2019
[Effect of acupuncture on pattern visual evoked potential of cerebral visual impairment in children aged 3-10 years]
Xue-Qing Zhao1, Cong Zhang2, Han-Jun Sun3
1Department of Pediatrics, Chongqing Hospital of TCM, Chongqing 40021, China.
Insights
Acupuncture combined with visual stimulation significantly improves visual acuity and pattern visual evoked potential (P-VEP) in children with cerebral visual impairment (CVI). This combined therapy offers superior clinical effects compared to conventional visual stimulation alone.
Area of Science:
- Ophthalmology
- Neurology
- Integrative Medicine
Background:
- Cerebral visual impairment (CVI) affects children's visual development.
- Conventional visual stimulation is a standard treatment for CVI.
- Evaluating novel therapeutic approaches for CVI is crucial.
Purpose of the Study:
- To assess the clinical efficacy of acupuncture combined with conventional visual stimulation in pediatric CVI.
- To investigate the impact of this combined therapy on pattern visual evoked potential (P-VEP) parameters.
Main Methods:
- Sixty children (3-10 years) with CVI were randomized into control (conventional visual stimulation) and observation (acupuncture + conventional visual stimulation) groups.
- Acupuncture was applied to specific acupoints (e.g., Baihui GV 20, Jingming BL 1) three times weekly for four weeks per course, with three courses total.
- Visual acuity and P-VEP were compared between groups before and after treatment.
Main Results:
- Both groups showed improved P-VEP incubation period (P100-L) and amplitude (P100-A) post-treatment (P<0.05).
- The observation group exhibited significantly greater improvements in P-VEP parameters compared to the control group (P<0.05).
- The observation group achieved a higher percentage of best-corrected visual acuity (0.6-0.8) post-treatment and at one-year follow-up (P<0.05).
Conclusions:
- Acupuncture combined with conventional visual stimulation effectively improves P-VEP and visual acuity in children with CVI.
- This integrated approach demonstrates superior clinical outcomes over conventional visual stimulation alone.
- The findings support acupuncture as a valuable adjunct therapy for pediatric CVI.
Objective:
To observe clinical effect of acupuncture combined with conventional visual stimulation on cerebral visual impairment (CVI) in children aged 3-10 years and influence on the pattern visual evoked potential (P-VEP).
Methods:
A total of 60 cases of children aged 3-10 years with CVI were randomly divided into an observation group and a control group, 30 cases in each group. The children in the control group received conventional visual stimulation therapy, 1 month as a course of treatment. On the basis of the control group, the children in the observation group was treated with acupuncture at Baihui (GV 20), Jingming (BL 1), Taiyang (EX-HN 5), Sibai (ST 2), etc. 3 times a week, and the treatment was given 4 weeks continuously as a course. Both groups received 3 courses of treatment. The visual acuity and P-VEP improvement were compared between the two groups before and after treatment.
Results:
After treatment, the incubation period (P100-L) of the two groups was shorter than before treatment, and the amplitude (P100-A) was higher than before treatment (P<0.05); and the degree of above changes in the observation group was lager than the control group (P<0.05). The percentage of best corrected visual acuity of 0.6-0.8 in the observation group after treatment and follow-up 1 year after treatment was higher than before treatment (P<0.05), and was higher than the control group (P<0.05).
Conclusion:
Acupuncture combined with conventional visual stimulation can improve the incubation period (P100-L) and amplitude (P100-A) of P-VEP in children with CVI, and improve the best corrected visual acuity in children, the clinical effect is better than the conventional visual stimulation alone.
