Related Experiment Video
Updated: Nov 18, 2025

Accessing the Cytotoxicity and Cell Response to Biomaterials
Published on: July 8, 2021
Toxic Metals Content in Impacted Third Molars and Adjacent Bone Tissue in Different Groups of Patients
Ewelina Bryła1, Maciej Dobrzyński2, Damian Konkol3
1Private Dental Clinic Maciej Kozlowski, Spokojna 23, 56-400 Olesnica, Poland.
Abstract:
The aim of the study was to determine the content of: Pb, Cd, Cr, Ni, Fe, Mn, Cu, Zn in the impacted third molars and a fragment of covering bone. Patients were divided according to following criteria: place of residence, age, gender, anatomical location of the removed tooth. Content of Cd, Pb, and Mn in the samples increases with age of the patient. The content of Cd and Pb in the tooth and bone was higher in patients living in Wroclaw. Residents of the Wroclaw had higher Cu content in the teeth, while they had a lower content in the jawbone. In contrast to Cd and Pb, an average of 68% higher concentration of Zn in the jawbone than in the tooth was noted. The content of Cr in tooth was lower by 33% than in the mandible bone and, similarly to the content of Ni, it decreased with age. In women, the Fe content in bone of the jaw was higher than in the removed tooth. The presence of Pb and Cd aggregates is confirmed in all hard tissues of the tooth and bone, in contrast to bioelements which show a stronger tendency to aggregate, essentially within the dentine.

