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EQ-5D-Y Value Set for Slovenia.

Valentina Prevolnik Rupel1, Marko Ogorevc2,

  • 1Institute for Economic Research, Kardeljeva ploščad 17, 1000, Ljubljana, Slovenia. rupelv@ier.si.

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Slovenia now has an EQ-5D-Y value set for children and adolescents, enabling quality-adjusted life-year (QALY) calculations. This study provides the world's first EQ-5D-Y-3L value set, crucial for health economics research.

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Area of Science:

  • Health Economics
  • Psychometrics
  • Paediatric Health Outcomes

Background:

  • A specific value set for the EuroQoL 5-Dimensions 3-Levels (EQ-5D-3L) Youth version (EQ-5D-Y) is unavailable in Slovenia.
  • This absence prevents the calculation of quality-adjusted life-years (QALYs) for children and adolescents using this health instrument.

Purpose of the Study:

  • To derive adult preferences for EQ-5D-Y health states in Slovenia.
  • To establish the first EQ-5D-Y-3L value set globally for use in QALY calculations.
  • To enable health economic evaluations for paediatric populations in Slovenia.

Main Methods:

  • An online discrete-choice experiment (DCE) survey involving 1074 Slovenian adults.
  • Composite time trade-off (cTTO) interviews with 200 participants to address the latent scale issue.
  • Estimation of the value set using a mixed (random coefficients) logit model.

Main Results:

  • All estimated model coefficients were statistically significant and exhibited expected negative signs.
  • Pain/discomfort was identified as the most impactful health dimension in the EQ-5D-Y.
  • Anxiety/depression, usual activities, and mobility were also significant dimensions, with self-care being the least important.

Conclusions:

  • This study successfully generated the EQ-5D-Y value set for Slovenia, filling a critical research gap.
  • This represents the world's first published EQ-5D-Y-3L value set, vital for QALY calculations in paediatric populations.
  • The findings facilitate robust health economic assessments for children and adolescents in Slovenia and potentially other regions.