Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Problem solving ability of parkinsonians.

M Alberoni1, S Della Salla, C Pasetti

  • 1Clinica Neurologica I dell'Università di Milano.

Italian Journal of Neurological Sciences
|February 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Technology-enhanced multi-domain at home continuum of care program with respect to usual care for people with cognitive impairment: the Ability-TelerehABILITation study protocol for a randomized controlled trial.

BMC psychiatry·2016
Same author

Follow-up of 53 Alzheimer patients with the MODA (Milan Overall Dementia Assessment).

Behavioural neurology·2014
Same author

C rossmodal agnosia for familiar people as a consequence of right infero polar temporal atrophy.

Cognitive neuropsychology·2010
Same author

Oxidative imbalance in different neurodegenerative diseases with memory impairment.

Neuro-degenerative diseases·2010
Same author

Communicating medical information: a little lesson from Italian patients.

Giornale italiano di medicina del lavoro ed ergonomia·2010
Same author

Functional living skills assessment: a standardized measure of high-order activities of daily living in patients with dementia.

European journal of physical and rehabilitation medicine·2010
Same journal

Attualità in neurochirurgia : Edited by P. Paoletti, R. Kneich, R. Urcioli, C. Spairani Atti del XXXV Congresso Nazionale della Società Italiana di Neurochirurgia, September 1986. Mondadori Editore, 829 pages.

Italian journal of neurological sciences·2016
Same journal

24th Annual Meeting of the Italian Neuropathological Association : May 26-27-28, 1988 Napoli, Castel dell'Ovo.

Italian journal of neurological sciences·2016
Same journal

[Not Available].

Italian journal of neurological sciences·2016
Same journal

[Not Available].

Italian journal of neurological sciences·2016
Same journal

Pathogenesis and surgical treatment of neurovascular primary headaches.

Italian journal of neurological sciences·2016
Same journal

The complementary contribution of the rhinologist and the neurologist at the clinical study and treatment of the cluster headache.

Italian journal of neurological sciences·2016
See all related articles

Cognitive issues in Parkinson

Area of Science:

  • Neuroscience
  • Neurology
  • Cognitive Science

Background:

  • Parkinson disease (PD) is a neurodegenerative disorder primarily affecting motor function.
  • Cognitive impairment is common in PD, but its underlying mechanisms remain debated.
  • The role of nigrostriatal dopaminergic deficits in cognitive dysfunction in early PD is unclear.

Purpose of the Study:

  • To test the hypothesis that cognitive defects in nondemented, nondepressed Parkinson's patients are solely due to nigrostriatal motor slowing.
  • To investigate the relationship between motor slowing and problem-solving ability in early Parkinson's disease.

Main Methods:

  • A simplified London Towers Test assessed problem-solving ability in 26 mildly disabled Parkinson's patients.
  • Patients were optimally treated with L-Dopa, nondemented, nondepressed, and without anticholinergic medication.

Related Experiment Videos

  • Performance was compared to 131 healthy controls.

    • Main Results:

    • No significant difference in problem-solving ability was found between Parkinson's patients and healthy controls.
    • The results did not support the hypothesis linking cognitive defects solely to nigrostriatal motor slowing.

    Conclusions:

    • The study provides no evidence that cognitive deficits in early Parkinson's disease are exclusively caused by nigrostriatal dopaminergic dysfunction leading to motor slowing.
    • Alternative or additional mechanisms may underlie cognitive impairment in Parkinson's disease.