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Anticoagulant-related nephropathy: A case report
Kee Tat Lee1, Wan Syahira Wan A Kammal2, Boon Huei Kong3
1Department of Medicine, Hospital Pulau Pinang, Pulau Pinang, Malaysia.
Summary
Anticoagulant-related nephropathy (ARN) is an underdiagnosed kidney disease complication of blood thinners. This case highlights ARN diagnosis in a patient with over-anticoagulation and acute kidney injury during warfarin therapy.
Area of Science:
- Nephrology
- Hematology
- Internal Medicine
Background:
- Anticoagulant-related nephropathy (ARN) is a recently identified kidney disease.
- ARN is an underdiagnosed complication associated with anticoagulant therapy.
- Widespread use of anticoagulants contrasts with the rarity of ARN reports.
Observation:
- A 64-year-old male patient presented with signs of over-anticoagulation.
- The patient was undergoing warfarin therapy for deep-vein thrombosis in his left lower limb.
- He exhibited acute on chronic kidney injury.
Findings:
- Renal biopsy was performed to investigate the kidney injury.
- Biopsy results confirmed the diagnosis of anticoagulant-related nephropathy (ARN).
Implications:
- This case underscores the importance of considering ARN in patients with kidney injury and anticoagulation.
- Accurate diagnosis of ARN is crucial for appropriate patient management.
- Further research may elucidate the pathophysiology and prevalence of ARN.
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