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New paulomycins produced by Streptomyces paulus
A D Argoudelis1, L Baczynskyj, W J Haak
1Upjohn Company, Kalamazoo, Michigan 49001.
The Journal of Antibiotics
|February 1, 1988
Abstract:
Paulomycin A2 (C34H46N2O17S), paulomycin C (C32H42N2O17S), paulomycin D (C31H40N2O17S), paulomycin E (C29H36N2O16S) and paulomycin F (C29H38N2O16S) have been isolated from fermentations of Streptomyces paulus strain 273. The structure of these compounds was determined using NMR and mass spectroscopic techniques. The new paulomycins, like paulomycins A and B (J. Antibiotics 35: 285-294, 1982) are highly active mainly against Gram-positive organisms.